• Blood sample
  • Submitted on 21/05/2025

24h Urine Test: High Creatinine, Low Urea - What Does It Mean?

I just did a 24 hour urine collection with blood sample. eGFR is 125, I drank 2.4L of water in the 24 hour period and had 1.625L of urine output. But the thing is my creatinine was 169 mL/min/1.73m2 when normal range according to lab is 88-135. Also my urea was 1124mg/dL or 18g/24h when normal range according to lab is 1710-3570mg/dL or 25.8-42.6g/24h. I'm in a bit of panic as these seem very low in comparison to normal range and I'm only seeing my urologist in a month from now. Please help me out explaining this so I can calm down a bit. Thanks in advance.

1 specialist answered

  • You do not appear to be in kidney failure, and there are no urgent red flags in these results. The combination of a high-normal eGFR, slightly elevated creatinine clearance, and lower urea points more toward dietary or physiological variation, not disease. It’s very reasonable to feel concerned when lab numbers don’t line up with the reference ranges, but the full picture here is actually quite reassuring.
    If anything still feels off to you — like fatigue, swelling, changes in urination, or other symptoms — bring them up with your doctor. And if you're particularly concerned about kidney function rather than structural issues, you mig
    ... Read more

    Agnieszka Pozdzik

    Nephrologist

    Waterloo

The content of the answers is strictly informative and should not be considered a substitute for medical advice

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